A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression

To address this hurdle, researchers from California State University Northridge developed an improved methodology for extracting high-quality RNA from FFPE samples. By briefly integrating a newly-designed micro-homogenizing (mH) tool with commercially available FFPE RNA extraction protocols, RNA recovery is increased by approximately 3-fold while maintaining standard A260/A280 ratios and RNA quality index (RQI) values. Furthermore, the researchers demonstrate that the mH-purified FFPE RNAs are longer and of higher integrity.

http://www.rna-seqblog.com/a-novel-method-for-rna-extraction-from-ffpe-samples-reveals-significant-differences-in-biomarker-expression/

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