Vectorborne diseases

  1. Selected Insect-borne diseases
  2. Selected Arachnid-borne diseases
  3. Selected Zoonoses

 

 

 

 

 

 

 

 

 

Selected Insect-borne diseases  

Since vectorborne disease include both insects (especially mosquitoes) and arachnids (ticks and mites), it is more appropriate to collectively refer to these diseases as arthropod borne diseases (sometimes abbreviated as arbo -- for example, an arbovirus is an arthropod borne virus). Among the true insectborne diseases, we begin this section with a disease spread by the blackfly, and then survey the wide range of mosquito borne diseases.

 

   1. Onchocerciasis (river blindness)
 
      agent:            Onchocerca volvulus (nematode, or roundworm)
      reservoir:         mostly humans
      transmission:      bite of infected female blackfly
                         (genus Similium) biological vector 
      symptoms:          chronic, nonfatal (incubation 1 year or more)
                         intense itching, impaired vision
 
A. mosquito-borne                                                     
                                                                         
   2. human malarias                                                     
                                                                         
      agent:             a parasitic protozoan in the Plasmodium genus                                      
      reservoir:         mostly humans and infected mosquitoes                      
      transmission:      Anopheles mosquites                     
      symptoms:          fever, chills, sweats                           
                         CNS effects (headache, delirium, coma)          
 
   3. filariasis                                                         
                                                                         
      agent:             Wuchereria or Brugia genus (nematodes, or roundworms) 
      reservoir:         humans                                             
      transmission:      mosquitoes (Aedes, Anopheles, or Culex)
                         (The mosquito carries the microscopic larval stage 
                         of the worm)      
      symptoms:          asymptomatic;   fever, asthma                                   
                         elephantiasis in chronic cases (enlarged limbs) 
                                                                                
   4. yellow fever:      one of the few immunizations required for 
                         travel in endemic areas                                                    
                                                                         
      agent:             yellow fever virus (a flavivirus)               
      reservoir:         humans (sometimes monkeys) and mosquitoes       
      transmission:      Aedes mosquito                          
      symptoms:          sudden onset of fever, jaundice, 
                         headache, backache, vomiting, diarrhea                 
                                                                         
   5. dengue fever (also called breakbone fever)                                           
                                                                         
      agent:             Dengue virus                                    
      reservoir:         human, infected mosquitoes                      
      transmission:      Aedes mosquitoes                                
      symptoms:          headache, joint and muscle pain, rash
                         with low case fatality rate           
                                                                         
   6. Arthropod-born viral encephalitis                                  
                                                                         
      agents:            Eastern equine encephalitis, Western equine encephalitis, 
                         California encephalitis, West Nile virus, etc.                   
      reservoir:         unknown for most agents                         
                         (possibly birds, rodents, bats, reptiles) 
                         found in more temperate areas (e.g., North America)      
      transmission:      Culex mosquitoes, possibly Aedes and others  
      symptoms:          often asymptomatic                              
                         inflammation of brain, spinal cord, meninges    
                         headache, fever, convulsions, paralysis, coma   
 
  
 
 

Selected Arachnid-borne diseases

                                                                                          
A. Tick-borne                                                         
                                                                         
   1. Rocky mountain spotted fever (tickborne typhus fever)                                     
                                                                         
      agent:             Rickettsia rickettsii
      reservoir:         dogs, rodents, other animals                    
      transmission:      bite of infected ticks (various species)
                         tick must be attached 4-6 hours       
      symptoms:          maculopapular rash (bumpy spots on the skin)
                         fever, headache, malaise, chills, rash, death   
                                                                                                 
   2. Tularemia: discovered in Tulare County, California                                                          
                                                                         
      agent:             Francisella tularensis (related to plague bacteria)
      reservoir:         wild animals (rabbits, muskrats, squirrels);
                         this disease is mostly a disease of animals, 
                         and is sometimes known as "rabbit fever"                 
      transmission:      bite of deer flies or wood ticks,                    
                         handling or ingestion of infected animals       
      symptoms:          typically: swollen lymph nodes, gastroenteritis
                         untreated, it can be fatal     
                                                                         
   3. Colorado tick fever                                                
                                                                         
      agent:             Colorado tick fever virus (an arbovirus)                     
      reservoir:         small animals (squirrels, chipmunks, porcupine) 
      transmission:      infected ticks:  Dermacentor andersoni
      symptoms:          similar to Dengue fever (joint and muscle pain; headache, fever, rash)                       
                                                                         
   4. Q fever            (first found in Queensland, Australia)                                                    
                                                                         
      agent:             Coxiella burneti (a rickettsia)                   
      reservoir:         ticks, various wild and domestic animals        
      transmission:      raw milk from infected cows, or direct contact with infected animals 
      symptoms:          typically: chills, headache; low case fatality                     
                                                                         
   5. Relapsing fever                                                    
                                                                         
      agent:             Borrelia recurrentis (a spirochete)               
      reservoir:         from lice: human;     from ticks: rodents        
      transmission:      lice or ticks                               
      symptoms:          gets its name from a fever that disappears and 
                         reappears, rash also 
 
   6. Lyme disease       discovered in 1975 in Lyme, Connecticut, it appeared 
                         as a cluster of arthritis cases in children as well as adults    
   agent:            Borrelia burgdorferi (discovered by Wally Burgdorfer)
                     this agent is a spirochete                     
   reservoir:        nymphs and adult ticks are found on white tailed deer
                     larval ticks are found on white footed mice 
   transmission:     deer ticks (Ixodes genus) 
   symptoms:         it starts with a blemish that resembles a blood blister in a "bulls-eye" pattern;
                     it then develops into flu-like symptoms, later into arthritis;
                     advanced cases can include heart disease and various neurological effects;
                     it is curable at all stages with antibiotics, but the joint degenerations that 
                     is associated with the arthritis may be irreversible. 
   controls:         control the ticks!
                     stay on trails when hiking; use repellants; stay covered whenever possible;
                     inspect for ticks frequently;
                     remove ticks using a tweezer on the mouth parts with a steady pull
                     (easier said than done!)  
                                 
                                            
                                                                         
B. Mite-borne                                                         
                                                                         
   7. Scrub typhus       (also known as mite-borne typhus)                                                     
                                                                         
      agent:             Rickettsia tsutsugamushi
      reservoir:         infected larval mites (chiggers), wild rodents             
      transmission:      mite bites                                      
      symptoms:          skin ulcer at site of bite, maculopapular rash, 
                         headache            
                                                                         
   8. Scabies            (sarcoptic itch, acariases)                               
                                                                         
      agent:             Sarcoptes scabiei (a mite)                      
      reservoir:         humans                                          
      transmission:      skin to skin, clothing, bedding;  
                         mites can burrow into skin in < 3 minutes   
      symptoms:          itching, lesions  
                         there are various drugs for treating mites, 
                         but they are always more effective with thorough daily bathing,
                         and laundering of all clothing and bedding                              
 
 
 
 

Selected Zoonoses

1. Zoonoses:        diseases and infections transmitted between 
                     vertebrate animals and humans                        
 
                                                                      
2. Plague:
                                                                      
   agent:             Yersinia pestis                                
   reservoir:         wild rodents (especially squirrels)               
   transmission:      Bubonic plague is spread by flea bite 
                          (especially Xenopsylla cheopis, the Oriental rat flea) 
                          These fleas can spread from rats to pets (dogs and cats)    
                      Pneumonic plague is spread person to person 
                          (respiratory route)  
   symptoms:          swollen lymph nodes (buboes), fever, pneumonia 
                          the pneumonic form is particularly virulent         
                                                                      
 
3. Murine typhus fever (also called endemic typhus or flea-borne typhus):                       
                                                                      
   agent:             mainly Rickettsia typhi                         
   reservoir:         rodents, fleas,                         
   transmission:      bite or feces of Oriental rat flea (Xenopsylla cheopis)  
   symptoms:          headache, chills, fever with low case fatality rate                         
 
4. Leptospirosis: 
                                                                      
   agent:             Leptospira interrogans (a spirochete)                                 
   reservoir:         farm animals and pets;                          
                      usually rats and other rodents                  
   transmission:      contact of skin with water, soil or vegetation  
                      contaminated by rodent urine! 
   symptoms:          may be asymptomatic,                            
                      fever, headache, chills, malaise, vomiting     
 
5. Psittacosis:       found worldwide but very often unrecognized 
                      sometimes called parrot fever (psittacos = parrot)
 
   agent:             Chlamydia psittaci
   reservoir:         birds (pigeons, parrots, parakeets,              
                             turkeys, ducks)                           
   transmission:      airborne (inhaling dried droppings)          
                      person to person is rare                     
                      incubation 4-15 days (usually about 10 days)
   symptoms:          varies (fever, headache, chills, sometimes cough) 
 
6. Rabies:   
 
   agent:             rabies virus                    
   reservoir:         1. skunks             2. bats and racoons       
                      3. foxes              4. dogs, cats, cattle 
                      squirrels are rarely infected with rabies
   transmission:      mainly animal bites, or licks on wounds                       
                      rarely: scratches, airborne, person to person 
   symptoms:          untreated, almost always fatal
                      fever, 
                      neurological:  paralysis, inflamation of the brain
                                     spasms in throat, leading to "hydrophobia" (fear of water),
                                     resulting in foaming at the mouth typical in rabid animals
                                     and the appearance of choking
   controls:          vaccinate pets and high-risk humans (e.g., veterinarians)
                      keep your distance from wild animals that appear to be choking!
                           (sadly, well meaning animal-lovers have ended up with rabies)
                      if you are bitten by a wild animal, retain the animal's head, if possible, for testing
                      if pets are bitten, re-vaccinate
                      if pets are unvaccinated, pets must often be destroyed
                      however, it's possible to detain the pet for 6 months and, 
                           if there are no behavioral changes, the animal can be released
                                 
 
6. Hantavirus:        hantavirus made big news in the 1990's because of its high case fatality 
                      in young healthy people in the U.S., and because the treatment options are limited.
                      The key is rodent control!
 
   agent:             hantavirus                             
   reservoir:         deer mice (but not urban rodents) 
   transmission:      inhaling airborne virus from mice droppings
   symptoms:          flu-like symptoms;  breathing difficulties; related to the hemorrhagic fevers
   controls:          control the mice:
                      open windows to ventilate closed areas
                      do not vacuum or sweep (instead, use a wet mop)
                      use mouse traps and other mice controls
                                 
 
      

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