1.
Loss of p53 stops
checkpoint control at broken chromosomes
2.
Different tumors have
different alterations Fig 23-41
3.
CANCER AQUIRED
CAPABILITIES
4.
Figure 21.8 Phenotypes of Mice with Mutations Along
the Pigment Synthesis Pathway can lead to melanoma as well
5.
All
factors together in cancer production Fig 23-31
6.
Knockout Fig 8-70
7.
Knockout Fig 8-70
8.
ACUTE
INFLAMATORY RESPONSE
9.
SEQUENCE
OF EVENTS
10.
PAF
AND T-CELL ADHESION
11.
Figure
42.17 Atherosclerosis: normal artery
and artery with plaque
12.
MAST
CELL SYNTHESIS AND SECRETION
13.
INFLAMATION
MEDIATORS
14.
RAS
GENES IN CANCER
15.
CONNECTION
OF INFLAMATION TO CANCER
16.
BREAST
CANCER CELLS MAKE CSF-1, ATTRACTING MACROPHAGES
17.
MACROPHAGES
BOOST TUMOR GROWTH
18.
Wnt
signaling path in cancer and stem cells
19.
Beta-catenin
suppression
20.
Tcf/Lef
transcription factors
21.
Stemcell
to differentiated cell types
22.
Ephrin gradients set
boundaries, controled by Wnt signals.
APC is an oncogene, mutations can be inherited
23.
Reported
Wnt effects
24.
Normal
vs deregulated Wnt
25.
Wnt
and leukemia-cancers develop in proliferating cells
26.
VIRAL
INDUCED CANCERS
27.
DIETARY
CANCER PREVENTION
28.
TUMOR
INDUCED ANGIOGENESIS
29.
Zinc-finger
protein+siRNA works better than each alone
30.
FORMATION
OF siRNA
31.
SILENCER shRNA CONSTRUCT
for K ion channel gene-TASK
32.
FORMS
OF RNA SILENCING
33.
RNA
MEDIATION OF HETEROCHROMATIN
34.
8-64
35.
Fig
8-65
36.
8-66